文章摘要
Molding Technology and Application of Balloon Catheter Made of Natural Latex and Silicone Rubber
Received:April 14, 2020  Revised:April 14, 2020
DOI：10.12136/j.issn.1000-890X.2021.07.0552
Key Words: natural latex；silicone rubber；balloon；catheter；molding technology；retention；biocompatibility；security
Author NameAffiliationE-mail
LI Zhifeng* Agriculture Products Processing Research Institute,Chinese Academy of Tropical Agricultural Sciences；Guangdong Provincial Key Laboratory of Natural Rubber Processing lizhifeng1207@163.com 
TAO Jinlong Agriculture Products Processing Research Institute,Chinese Academy of Tropical Agricultural Sciences；Guangdong Provincial Key Laboratory of Natural Rubber Processing  
KONG Na Agriculture Products Processing Research Institute,Chinese Academy of Tropical Agricultural Sciences；Guangdong Provincial Key Laboratory of Natural Rubber Processing  
ZHAO Pengfei Agriculture Products Processing Research Institute,Chinese Academy of Tropical Agricultural Sciences；Guangdong Provincial Key Laboratory of Natural Rubber Processing  
GUAN Jie Agriculture Products Processing Research Institute,Chinese Academy of Tropical Agricultural Sciences；Guangdong Provincial Key Laboratory of Natural Rubber Processing  
DING Hongda Agriculture Products Processing Research Institute,Chinese Academy of Tropical Agricultural Sciences；Guangdong Provincial Key Laboratory of Natural Rubber Processing  
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Abstract:
      Balloon catheters were widely used in clinical treatment．The performance，molding process and application of balloon catheter produced by natural latex and silicone rubber were compared． Natural latex showed excellent comprehensive properties，which was suitable for the multiple-stage impregnation processes to produce various types of balloon catheters with different specifications．However，the products of natural latex had poor biological compatibility．Typically，balloon catheter made of natural latex had many safety risks in clinical medicine，including allergies，nitrosamine-induced carcinogenesis and stimulations from residual calcium nitrate． Balloon catheters made of silicone rubber had excellent biocompatibility and safety in clinic，and had long retention time，but the price was relatively high．These two kinds of balloon catheters had their own market demands，and it was expected that balloon catheters made of natural latex would be gradually replaced by those made of silicone rubber．
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